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Directly observing therapy: a new view of drug tolerance in tuberculosis.
Philips, Jennifer A; Ernst, Joel D.
Afiliação
  • Philips JA; Division of Infectious Diseases, Department of Medicine, New York University School of Medicine, 522 First Avenue, Smilow 901, New York, NY 10016, USA.
Cell ; 145(1): 13-4, 2011 Apr 01.
Article em En | MEDLINE | ID: mdl-21458661
ABSTRACT
Drug tolerance in bacteria is widely believed to be due to metabolic changes that accompany growth arrest. A study in this issue of Cell reveals a drug tolerance mechanism in replicating mycobacteria that is induced by residence in macrophages and depends on drug efflux.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2011 Tipo de documento: Article