Ambulatory quantitative waking and sleeping cough assessment in patients with cystic fibrosis.
J Cyst Fibros
; 10(3): 193-200, 2011 May.
Article
em En
| MEDLINE
| ID: mdl-21459051
ABSTRACT
BACKGROUND:
Although cough is a commonly reported symptom, objective quantitation of cough during normal activity has not been performed in patients with CF.METHODS:
An ambulatory device was used to characterize cough over 24 hours. Pulmonary function and subject-reported coughing were also assessed.RESULTS:
Patients included 19 clinically stable adults with CF (malesfemales=109; median age [range]=26 [19-57] years; median %-predicted FEV(1) [range]=65 [44-106]%). Median [range] cough rate was 27 [13-66] coughs/hour, with values while awake of 41 [20-102] and while asleep of 2 [0.1-7] (p<0.0001, Wilcoxon signed-rank test). Subjective reporting was consistent with objective data for wake-sleep differences, but correlated poorly with objective waking cough rate.CONCLUSIONS:
Outpatient cough quantitation in patients with CF is feasible, indicates frequent coughing even during clinical stability, and may be useful in therapeutic trials in CF.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sono
/
Vigília
/
Monitorização Ambulatorial
/
Tosse
/
Fibrose Cística
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article