Supramolecular architectures self-assembled from asymmetrical hetero cyclopeptides.
Macromol Rapid Commun
; 32(9-10): 758-64, 2011 May 18.
Article
em En
| MEDLINE
| ID: mdl-21469242
ABSTRACT
In this study, two asymmetrical cyclopeptides (CP1 and CP2) were designed and synthesized. The self-assembly behaviors of the asymmetrical cyclopeptides at varying pHs were investigated in terms of transmission electron microscopy (TEM), circular dichroism (CD), and Fourier transform infrared (FT-IR) spectroscopy. It was found that the self-assembly of CP1 resulted in the formation of nanofibers with α-helix conformation, while CP2 self-assembled into well-ordered nanorods with anti-parallel ß-sheet conformation. The strategy demonstrated here presents great potential for preparation of well-defined nanostructures via rationally designing the molecular structures of cyclopeptides.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos Cíclicos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article