Synthesis, characterization and biological evaluation of some 16E-arylidene androstane derivatives as potential anticancer agents.
Steroids
; 76(7): 709-23, 2011 Jun.
Article
em En
| MEDLINE
| ID: mdl-21473874
ABSTRACT
A series of new 16E-arylidene androstane derivatives were synthesized and characterized. The new compounds were screened for their anticancer activities against the human cancer cell lines SW480, A549, HepG2 and HeLa in vitro using the MTT assay. The results of the in vitro study showed that a number of compounds have shown IC(50) values lower than 20 µM against the four cancer cell lines.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Androstanos
/
Antineoplásicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article