Synthesis of five nona-ß-(1â6)-d-glucosamines with various patterns of N-acetylation corresponding to the fragments of exopolysaccharide of Staphylococcus aureus.
Carbohydr Res
; 346(7): 905-13, 2011 May 15.
Article
em En
| MEDLINE
| ID: mdl-21474120
ABSTRACT
A series of five 3-acetamidopropyl ß-glycosides of nona-ß-(1â6)-glucosamines containing two N-acetylglucosamine residues separated by a different number of glucosamine units with free amino groups have been synthesized using a convergent blockwise approach. Oxazoline glycosylation was used to introduce N-acetylglucosamine residues. These nonasaccharides are structurally related to the poly-N-acetylglucosamine (PNAG) extracellular polysaccharide of Staphylococcus aureus and can be used as models for biochemical and immunological studies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligossacarídeos
/
Acetilglucosamina
/
Beta-Glucanas
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article