Blood lead levels of contemporary Japanese children.
Environ Health Prev Med
; 17(1): 27-33, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-21516304
ABSTRACT
OBJECTIVES:
Lead concentrations in whole blood (BPb) of Japanese children were measured to obtain insight into the sources of variation and to estimate health risk.METHODS:
Blood samples were taken from 352 children (aged 1-14 years) at pediatric clinics/hospitals in 3 regions of Japan (Tokyo, Shizuoka, and Osaka) during 2005-2006 (Shizuoka only) and 2008-2010 (3 regions), and BPb was measured by inductively coupled plasma mass spectrometry after acid digestion.RESULTS:
Geometric mean BPb of the 352 children was 1.07 µg/dL, among the lowest in the world. Based on this result, the probability of exceeding BPb 10 µg/dL, the action level proposed by the US Centers for Disease Control and Prevention, in general Japanese children was estimated to be negligible. There was a significant negative correlation between BPb and age, while sex difference was not significant. BPb was significantly lower in subjects in Tokyo than in the other two regions. Age-adjusted mean BPb was significantly higher in children with a family member who smoked in their presence than in those who did not have such a family member, indicating that passive smoking had a significant effect on BPb.CONCLUSIONS:
Health risk of lead exposure is minimal in Japanese children. To lower the exposure level further, reduction of passive smoking is suggested as one of the effective measures.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Poluição por Fumaça de Tabaco
/
Exposição Ambiental
/
Chumbo
/
Intoxicação por Chumbo
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
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Child
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Child, preschool
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Female
/
Humans
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Infant
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Male
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article