Dibenzocyclooctadiene lignans from the fruits of Schisandra rubriflora and their anti-HIV-1 activities.
J Asian Nat Prod Res
; 13(5): 393-9, 2011 May.
Article
em En
| MEDLINE
| ID: mdl-21534036
ABSTRACT
Two new dibenzocyclooctadiene lignans, rubrilignans A and B (1, 2), together with 17 known ones, were isolated from the fruits of Schisandra rubriflora. The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1 and 2 were also evaluated for their anti-HIV-1 activities and showed weak anti-HIV-1 activity with EC(50) values of 2.26 and 1.82 µg/ml, and therapeutic index values of 35.5 and 18.6, respectively.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Medicamentos de Ervas Chinesas
/
HIV-1
/
Lignanas
/
Fármacos Anti-HIV
/
Schisandra
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article