[Gingival hyperplasia as side effect of the calcium channel blocker amlodipine]. / Gingivahyperplasie als Nebenwirkung des Kalziumkanalblockers Amlodipin.

ABSTRACT

Medically induced gingival overgrowth is one of the major side effects of phenytoine, cyclosporine A and the channel blocker Nifedipine and it is well documented in various studies and case series. Recently an alternative channel blocker, Amlodipine, has been implemented into the clinical treatment of cardiovascular diseases. By means of a clinical case presentation it was shown that Amlodipine is able to induce gingival overgrowth in the oral cavity as well. Additionally, the causes of Amlodipine-induced gingival hyperplasia are critically discussed and several options of therapy modalities presented.