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[Airway complications following lung transplantation - clinic, diagnosis, and interventional management]. / Atemwegskomplikationen nach Lungentransplantation - Klinik, Diagnose und interventionelle Behandlung.
Kroegel, C; Hekmat, K; Möser, A; Happe, J; Walther, R; Reissig, A.
Afiliação
  • Kroegel C; Abt. Pneumologie & Allergologie/Immunologie, Medizinische Klinik I, Jena. claus.kroegel@med.uni-jena.de
Pneumologie ; 65(5): 293-307, 2011 May.
Article em De | MEDLINE | ID: mdl-21557142
ABSTRACT
Tracheobronchial complications following lung transplantation are defined as local structural or infectious alterations of the airways, which occur early or several months after lung transplantation (LTx). They preferentially develop in the region of the bronchial anastomosis. The most frequently reported complications are bronchial stenosis, bronchial dehiscence, exophytic excessive granulation tissue formation, tracheo-bronchomalacia, bronchial fistulas, and endobronchial infections. Airway complications are mainly attributed to ischaemia of the donor bronchus during the immediate post-transplant period. The most relevant risk factors for the development of airway complications include local infections, surgical techniques, and the immunosuppressive regimen. Thus, management of post-transplant bronchial complications requires early interventional bronchoscopic procedures including balloon bronchoplasty, cryotherapy, laser photoresection, endobronchial brachytherapy, and bronchial stents. In addition, antibiotic treatment, or non-invasive positive-pressure ventilation may be necessary. The procedures required depend on the time of occurrence, the type, and clinical relevance of the airway complication. This review summarises clinical presentation, risk factors, the diagnostic methods as well as management options for the most common LTx-associated airway complications.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Respiratórios / Doenças da Traqueia / Broncopatias / Transplante de Pulmão Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: De Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtornos Respiratórios / Doenças da Traqueia / Broncopatias / Transplante de Pulmão Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: De Ano de publicação: 2011 Tipo de documento: Article