A novel treatment approach for paediatric Gorham-Stout syndrome with chylothorax.
Acta Paediatr
; 100(11): 1448-53, 2011 Nov.
Article
em En
| MEDLINE
| ID: mdl-21605166
ABSTRACT
AIM:
To expand the treatment options in paediatric Gorham-Stout syndrome (GSS) when conventional therapy is ineffective.METHOD:
Two children with biopsy confirmed GSS, a rare disorder with progressive lymphangiomatosis, were treated with a combination of interferon-α-2b, low anticoagulant, low molecular weight heparin, radiotherapy and surgery.RESULTS:
The combined therapy resolved the symptoms in the acute phase, and both patients have since been free of symptoms for >2 years.CONCLUSION:
The successful addition of a low anticoagulant, low molecular weight heparin (tafoxiparin) to the treatment protocol in two paediatric cases of the GSS may justify the use of this approach in similar cases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Osteólise Essencial
/
Quilotórax
/
Linfangioleiomiomatose
Tipo de estudo:
Etiology_studies
/
Guideline
Limite:
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article