Heparan sulfate proteoglycans.
Cold Spring Harb Perspect Biol
; 3(7)2011 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-21690215
ABSTRACT
Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix, where they interact with a plethora of ligands. Over the last decade, new insights have emerged regarding the mechanism and biological significance of these interactions. Here, we discuss changing views on the specificity of protein-heparan sulfate binding and the activity of HSPGs as receptors and coreceptors. Although few in number, heparan sulfate proteoglycans have profound effects at the cellular, tissue, and organismal level.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores de Superfície Celular
/
Proteoglicanas de Heparan Sulfato
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article