Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison.
Angew Chem Int Ed Engl
; 50(35): 8077-81, 2011 Aug 22.
Article
em En
| MEDLINE
| ID: mdl-21751313
ABSTRACT
Capturing the right ligand at the right spot a well-balanced system for non-natural amino acid mutagenesis allows the ligand binding sites of a class II G-protein coupled receptor to be mapped and distinct binding domains to be identified for different ligands in the native environment of mammalian cells.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores Acoplados a Proteínas G
/
Aminoácidos
/
Ligantes
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article