Transdermal nicotine facilitates smoking cessation.
Clin Pharmacol Ther
; 47(3): 323-30, 1990 Mar.
Article
em En
| MEDLINE
| ID: mdl-2178852
ABSTRACT
The efficacy of a transdermal nicotine patch in facilitation of smoking cessation was evaluated in a randomized double-blind trial. Sixty-five smokers who were highly dependent on cigarettes participated in the study, which included a behavioral smoking-cessation program. The rates of continuous abstinence were significantly higher in the nicotine group both initially (55% versus 34%) and at 3 weeks (18% versus 6%). Certain smoking withdrawal symptoms, including negative affect and hypoarousal, were effectively relieved by the nicotine patch. There was a trend toward a reduction in cigarette craving, whereas hunger and habit withdrawal symptoms were not affected. The main side effect associated with the nicotine patch was skin irritation. These findings suggest that a nicotine skin patch may be a useful aid to smoking cessation; however, the combination of other techniques with nicotine replacement may provide a more effective treatment for symptoms such as craving for cigarettes.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tabagismo
/
Prevenção do Hábito de Fumar
/
Nicotina
Tipo de estudo:
Clinical_trials
Limite:
Female
/
Humans
/
Male
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article