Your browser doesn't support javascript.
loading
The role of the toxicologic pathologist in the biopharmaceutical industry.
van Tongeren, Susan; Fagerland, Jane A; Conner, Michael W; Diegel, Kelly; Donnelly, Kevin; Grubor, Branka; Lopez-Martinez, Alric; Bolliger, Anne Provencher; Sharma, Alok; Tannehill-Gregg, Sarah; Turner, Patricia V; Wancket, Lyn M.
Afiliação
  • van Tongeren S; Nonclinical Drug Safety US, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA.
Int J Toxicol ; 30(5): 568-82, 2011 Oct.
Article em En | MEDLINE | ID: mdl-21878555
ABSTRACT
Toxicologic pathologists contribute significantly to the development of new biopharmaceuticals, yet there is often a lack of awareness of this specialized role. As the members of multidisciplinary teams, toxicologic pathologists participate in all aspects of the drug development process. This review is part of an initiative by the Society of Toxicologic Pathology to educate scientists about toxicologic pathology and to attract junior scientists, veterinary students, and veterinarians into the field. We describe the role of toxicologic pathologists in identifying candidate agents, elucidating bioactive pathways, and evaluating efficacy and toxicity in preclinical animal models. Educational and specialized training requirements and the challenges of working in a global environment are discussed. The biopharmaceutical industry provides diverse, challenging, and rewarding career opportunities in toxicologic pathology. We hope that this review promotes understanding of the important role the toxicologic pathologist plays in drug development and encourages exploration of an important career option.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Patologia Clínica / Toxicologia / Biotecnologia / Médicos Veterinários / Indústria Farmacêutica Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2011 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Patologia Clínica / Toxicologia / Biotecnologia / Médicos Veterinários / Indústria Farmacêutica Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2011 Tipo de documento: Article