Treatment of imported severe malaria with artesunate instead of quinine--more evidence needed?
Malar J
; 10: 256, 2011 Sep 07.
Article
em En
| MEDLINE
| ID: mdl-21899729
ABSTRACT
Rapid and fast acting anti-malarials are essential to treat severe malaria. Quinine has been the only option for parenteral therapy until recently. While current evidence shows that intravenous artesunate is more effective than quinine in treating severe malaria in endemic countries, some questions remain regarding safety profiles and drug resistance. For imported severe malaria, additional unanswered questions are related to generalizability of the findings from endemic countries and to legal aspects, as there is no Good Manufacturing Practice-conform drug available yet. Here, the implications of existing evidence for the treatment of imported severe malaria are discussed.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artemisininas
/
Malária
/
Antimaláricos
Limite:
Humans
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article