Genetic linkage of C3H/HeJ and BALB/c endogenous ecotropic C-type viruses to phosphoglucomutase-1 on chromosome 5.

Ihle, J N; Joseph, D R; Domotor, J J

Ihle, J N; Joseph, D R; Domotor, J J.

Science ; 204(4388): 71-3, 1979 Apr 06.

Article em En | MEDLINE | ID: mdl-219476

ABSTRACT

ABSTRACT

The genetic linkage of the endogenous C3H/HeJ C-type ecotropic virus to phosphoglucomutase-1 (0.28, recombinant fraction) on chromosome 5 was established by means of serological assays of backcrossed mice. With a combination of serological techniques and DNA-DNA hybridization the BALB/c endogenous ecotropic virus was shown to be either closely linked or allelic with the C3H/HeJ locus.

Assuntos

Genes Virais; Camundongos Endogâmicos BALB C/microbiologia; Camundongos Endogâmicos C3H/microbiologia; Fosfoglucomutase/genética; Retroviridae/genética; Alelos; Animais; Genes; Ligação Genética; Vírus da Leucemia Murina/genética; Camundongos; Camundongos Endogâmicos/genética; Fenótipo

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoglucomutase / Retroviridae / Genes Virais / Camundongos Endogâmicos BALB C / Camundongos Endogâmicos C3H Limite: Animals Idioma: En Ano de publicação: 1979 Tipo de documento: Article

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