[Serum cortisol and ceruloplasmin determination in neonates with intrauterine growth retardation]. / Szérum cortisol és coeruloplasmin meghatározások intrauterin retardált újszülöttekben.
Orv Hetil
; 131(25): 1351-5, 1990 Jun 24.
Article
em Hu
| MEDLINE
| ID: mdl-2198509
ABSTRACT
The authors have shown recently that coeruloplasmin deficiency was associated with severe respiratory distress in premature neonates. In the present study they measured the serum cortisol and coeruloplasmin levels in 58 intrauterine growth retarded infants. The results were compared to the data of 44 appropriate for gestational age neonates. Both parameters showed association with the fetal distress in term babies (cortisol 17.2 vs 12.3 ug/100 ml, coeruloplasmin 29.7 vs 11.9 U/l). Coeruloplasmin activity was also higher in growth retarded prematures (48.5 vs 16.5 U/l), while cortisol concentration increased irrespective of intrauterine malnutrition. There was a significant positive correlation between serum cortisol and coeruloplasmin in dysmaturity. This is the first report suggesting a possible role for coeruloplasmin, an important extracellular antioxidant enzyme in the precocious development of intrauterine growth retarded infants.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ceruloplasmina
/
Hidrocortisona
/
Retardo do Crescimento Fetal
Limite:
Humans
/
Newborn
Idioma:
Hu
Ano de publicação:
1990
Tipo de documento:
Article