Determination of paracetamol based on its quenching effect on the photoluminescence of CdTe fluorescence probes.
J Fluoresc
; 22(2): 591-6, 2012 Mar.
Article
em En
| MEDLINE
| ID: mdl-22045407
ABSTRACT
L-Cysteine capped CdTe nanoparticles (NPs) were synthesized in aqueous medium, and their application as fluorescence probes in the determination of paracetamol was studied. The L-cysteine capped CdTe NPs were characterized by transmission electron microscopy, X-ray diffraction spectrometry, spectrofluorometry, ultraviolet-visible and Fourier transform infrared spectrometry. Based on the distinct fluorescence quenching of CdTe fluorescence probes in the presence of paracetamol, a simple, rapid and specific method for paracetamol determination was presented. Under optimum conditions, the relative fluorescence intensity of CdTe NPs was linearly proportional to paracetamol concentration from 1.0 × 10(-8) mol/L to 1.6 × 10(-7) mol/L with a detection limit of 4.2 × 10(-9) mol/L. The proposed method was applied to detect paracetamol in commercial tablets with satisfactory results.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Telúrio
/
Compostos de Cádmio
/
Luminescência
/
Corantes Fluorescentes
/
Acetaminofen
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article