3-[(1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-yl)amino]-benzoic acid.
Acta Crystallogr Sect E Struct Rep Online
; 67(Pt 8): o2150, 2011 Aug 01.
Article
em En
| MEDLINE
| ID: mdl-22091165
ABSTRACT
In the title compound, C(21)H(20)N(4)O(2), the statistically planar 1H-limidazole ring [maximum deviation = 0.003â
(1)â
Å] makes dihedral angles of 1.33â
(9) and 8.23â
(7)°, respectively, with the essentially planar fused pyridine ring [maximum devation = 0.018â
(1)â
Å] and the pendant benzene ring, which is attached to the pyridine ring by an -NH- group. An intra-molecular C-Hâ¯N inter-action, which generates an S(6) ring, helps to estalish the mol-ecular conformation. In the crystal, the mol-ecules are linked by N-Hâ¯O, C-Hâ¯O and O-H-N hydrogen bonds, which generate bifurcated R(1) (2)(6) and R(2) (2)(9) ring motifs, resulting in supra-molecular [001] chains. The crystal structure also features weak π-π stacking [centroid-centroid distance = 3.5943â
(9)â
Å] and C-Hâ¯π inter-actions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article