Effects of liver tumor and post-ablation necrosis volume on the result of radiofrequency ablation.
Hepatogastroenterology
; 59(117): 1537-40, 2012.
Article
em En
| MEDLINE
| ID: mdl-22172374
ABSTRACT
BACKGROUND/AIMS:
To find out whether the total tumor mass and post-ablation necrosis volume influence the disease-free survival of patients following radiofrequency ablation (RFA).METHODOLOGY:
Fifty nine patients with RFA of primary and secondary tumors were evaluated retrospectively in a four year period. Total liver mass, post-ablation necrosis volume and their ratio were evaluated using computed tomography examination in the relationship with the risk of insufficient tumor ablation and the disease-free patients survival.RESULTS:
A complete ablation was performed in 51 patients, non-ablation in 8 (13.6%) patients. Tumor, necrosis volume were 19.2±19.5, 58.7±44.7mL, respectively. The tumor and necrosis mass ratio was 0.39±0.45. The tumor or necroses mass volume or the tumor/necroses mass ratio had no effect on the patients progression-free survival. Patients with a necrosis volume <25mL had a 10-times higher risk of insufficient ablation (OR=9.9; 95% CI=1.9-51.5; p<0.002) and patients with the tumor/necrosis mass ratio >0.4 had a 8-times higher risk of insufficient ablation (OR=7.9; 95% CI=1.4-44.6; p<0.01).CONCLUSIONS:
Necrosis volume after RFA and tumor/necrosis mass ratio are the important factors for insufficient ablation but do not have any influence on the patients progression-free survival.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Colorretais
/
Ablação por Cateter
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Carcinoma Hepatocelular
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Fígado
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Neoplasias Hepáticas
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article