Increase of lifespan for glioma-bearing rats by using minibeam radiation therapy.
J Synchrotron Radiat
; 19(Pt 1): 60-5, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-22186645
ABSTRACT
This feasibility work assesses the therapeutic effectiveness of minibeam radiation therapy, a new synchrotron radiotherapy technique. In this new approach the irradiation is performed on 9L gliosarcoma-bearing rats with arrays of parallel beams of width 500-700 µm. Two irradiation configurations were compared a lateral unidirectional irradiation and two orthogonal arrays interlacing at the target. A dose escalation study was performed. A factor of three gain in the mean survival time obtained for some animals paves the way for further exploration of the different possibilities of this technique and its further optimization.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Encefálicas
/
Gliossarcoma
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article