Rapid reversal of uremic neuropathy following renal transplantation in an adolescent.
Pediatr Transplant
; 16(7): E296-300, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22188489
ABSTRACT
Clinical and pathologic studies on adults with uremic neuropathy are numerous, but less is known about this disorder in children and adolescents. We report the clinical, electrophysiologic, and pathologic findings in an adolescent female with uremic neuropathy. Electrophysiologic findings were consistent with a primarily axonal sensorimotor polyneuropathy. Sural nerve biopsy revealed areas of focal depletion in myelin sheaths and loss of axons. Axonal degeneration with secondary myelin changes appears to be the characteristic pathology in this case, one of the youngest to our knowledge for which nerve biopsy data are available. Our patient experienced dramatic recovery after renal transplantation, similar to the reports of older patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Polineuropatias
/
Uremia
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Glomerulosclerose Segmentar e Focal
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Transplante de Rim
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Insuficiência Renal
Tipo de estudo:
Etiology_studies
Limite:
Adolescent
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Female
/
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article