Note: Integration of trapped ion mobility spectrometry with mass spectrometry.
Rev Sci Instrum
; 82(12): 126106, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-22225261
ABSTRACT
The integration of a trapped ion mobility spectrometer (TIMS) with a mass spectrometer (MS) for complementary fast, gas-phase mobility separation prior to mass analysis (TIMS-MS) is described. The ion transmission and mobility separation are discussed as a function of the ion source condition, bath gas velocity, analysis scan speed, RF ion confinement, and downstream ion optical conditions. TIMS mobility resolution depends on the analysis scan speed and the bath gas velocity, with the unique advantage that the IMS separation can be easily tuned from high speed (~25 ms) for rapid analysis to slower scans for higher mobility resolution (R > 80).
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espectrometria de Massas
/
Integração de Sistemas
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article