Dabigatran in clinical practice for atrial fibrillation with special reference to activated partial thromboplastin time.
Circ J
; 76(3): 755-7, 2012.
Article
em En
| MEDLINE
| ID: mdl-22293451
ABSTRACT
BACKGROUND:
The distribution of activated partial thromboplastin time (APTT) in nonvalvular atrial fibrillation (NVAF) patients under dabigatran therapy remains to be clarified. METHODS ANDRESULTS:
The study population was 196 NVAF patients who were treated with dabigatran in 2011 (126 with 220 mg/day). The APTT values showed a wide distribution among the patients, especially in those with a reduced dose, who seemed to show a high value even in patients without contraindications.CONCLUSIONS:
We found a wide distribution of APTT in NVAF patients under dabigatran treatment. High APTT might help screen for bleeding risks among patients under dabigatran, but requires future investigation.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tempo de Tromboplastina Parcial
/
Fibrilação Atrial
/
Benzimidazóis
/
Beta-Alanina
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article