Evaluation of n-butyl cyanoacrylate adhesive in rat subcutaneous tissue.
Dermatol Surg
; 38(5): 767-71, 2012 May.
Article
em En
| MEDLINE
| ID: mdl-22309142
ABSTRACT
BACKGROUND:
Tissue adhesives have been widely used for wound closure, especially in children, because they are painless, fast, and easy to use and result in minimal scarring.OBJECTIVE:
To analyze the biocompatibility of an adhesive based on n-butyl-cyanoacrylate in the subcutaneous tissue of rats. MATERIALS ANDMETHODS:
Two surgical sites were prepared (approximately 3 cm apart) one on the left side of the animal and the other on the right side); polyethylene tubes were implanted in each surgical site. The tube on the left was filled with n-butyl-cyanoacrylate (treated group) and the tube on the right side was unfilled (control group). After 7, 30, and 120 days, the animals were killed, and the specimens were processed for histologic analysis.RESULTS:
No significant inflammatory reaction occurred in the treated group, showing results similar to the control group.CONCLUSION:
This adhesive based on n-butyl-cyanoacrylate is biocompatible in the subcutaneous tissue of rats.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Tela Subcutânea
/
Embucrilato
Tipo de estudo:
Evaluation_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article