A flow cytometry-based dopamine transporter binding assay using antagonist-conjugated quantum dots.
Chem Commun (Camb)
; 48(44): 5428-30, 2012 Jun 04.
Article
em En
| MEDLINE
| ID: mdl-22543630
ABSTRACT
Here we present the development and validation of a flow cytometry-based dopamine transporter (DAT) binding assay that uses antagonist-conjugated quantum dots (QDs). We anticipate that our QD-based assay is of immediate value to the high throughput screening of novel DAT modulators.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Piperazinas
/
Antagonistas de Dopamina
/
Proteínas da Membrana Plasmática de Transporte de Dopamina
/
Ensaios de Triagem em Larga Escala
Limite:
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article