Spontaneously occurring multicentric basal cell carcinoma and keratoacanthomas in a multimammate mouse (Mastomys spp.).
J Vet Diagn Invest
; 24(4): 696-701, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22585958
ABSTRACT
A multicentric basal cell carcinoma was diagnosed in a male multimammate mouse (Mastomys spp.) with widespread cutaneous alterations. Macroscopically, the skin was thickened and extremely wrinkled. Histopathological examination showed multicentric expanding cell-rich tumors composed of basaloid cells interpreted as basal cell carcinoma. Immunohistochemistry detected strong cytokeratin 14 positivity in the epidermal basal layer and in loosely arranged areas of these tumors but only a minimal positive reaction in densely packed areas of tumor cells. Furthermore, samples from the abdomen showed 3 nodular proliferations diagnosed as keratoacanthomas.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
/
Carcinoma Basocelular
/
Ceratoacantoma
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article