The contribution of antiphosphatidylethanolamine antibodies in the diagnosis of the antiphospholipid syndrome.
Lupus
; 21(7): 727-8, 2012 Jun.
Article
em En
| MEDLINE
| ID: mdl-22635214
ABSTRACT
The diagnosis of seronegative antiphospholipid syndrome (APS) has been proposed for patients with well-defined clinical APS but persistently negative for the routinely tested antiphospholipid antibodies (aPLs) antibodies to cardiolipin (aCL) and to ß(2) glycoprotein I (aß(2)GPI) and lupus anticoagulant (LA). Antibodies directed to phosphatidylethanolamine (aPE) have been described as the sole aPLs in some patients with clinical manifestations of APS. Here, we briefly summarize the available data on the clinical associations of aPEs and propose their investigation in patients with a clinical profile highly suggestive of seronegative APS.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fosfatidiletanolaminas
/
Síndrome Antifosfolipídica
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article