Dna2 offers support for stalled forks.
Cell
; 149(6): 1181-3, 2012 Jun 08.
Article
em En
| MEDLINE
| ID: mdl-22682239
ABSTRACT
The ATR and ATM checkpoint kinases preserve the integrity of replicating chromosomes by preventing the reversal of stalled and terminal replication forks. Hu et al. now show that the ATR pathway targets the Dna2 nuclease to process stalled forks and counteract fork reversal.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article