HDX workbench: software for the analysis of H/D exchange MS data.
J Am Soc Mass Spectrom
; 23(9): 1512-21, 2012 Sep.
Article
em En
| MEDLINE
| ID: mdl-22692830
ABSTRACT
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is an established method for the interrogation of protein conformation and dynamics. While the data analysis challenge of HDX-MS has been addressed by a number of software packages, new computational tools are needed to keep pace with the improved methods and throughput of this technique. To address these needs, we report an integrated desktop program titled HDX Workbench, which facilitates automation, management, visualization, and statistical cross-comparison of large HDX data sets. Using the software, validated data analysis can be achieved at the rate of generation. The application is available at the project home page http//hdx.florida.scripps.edu .
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Proteínas
/
Medição da Troca de Deutério
/
Espectrometria de Massas em Tandem
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article