How I treat inhibitors in haemophilia.
Haemophilia
; 18 Suppl 4: 48-53, 2012 Jul.
Article
em En
| MEDLINE
| ID: mdl-22726083
ABSTRACT
The management of patients with inhibitors is the greatest challenge facing haemophilia health professionals. Immune tolerance induction (ITI) can be successful in eliminating the inhibitor in the majority of patients, provided it is started soon after the inhibitor develops and the titre of the inhibitor is <10 BU at commencement of ITI. Acute bleeding is treated using one of two bypassing agents, which exhibit similar efficacy and safety. Surgery in inhibitor patients is challenging and should only be carried out in experienced centres.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fator VIII
/
Coagulantes
/
Inibidores dos Fatores de Coagulação Sanguínea
/
Hemofilia A
/
Tolerância Imunológica
Limite:
Humans
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article