Discrepancy of calcium detection between gray scale intravascular ultrasound and spectral analysis of radiofrequency data.
Int J Cardiol
; 167(6): 2611-6, 2013 Sep 10.
Article
em En
| MEDLINE
| ID: mdl-22819606
ABSTRACT
BACKGROUND:
We evaluated discrepancy of calcium detection between gray scale intravascular ultrasound (IVUS) and virtual histology (VH)-IVUS and the association between coronary calcium and plaque composition.METHODS:
Study population consisted of 162 consecutive patients who underwent percutaneous coronary intervention with VH-IVUS study. Subjects were divided into 3 groups based on gray scale IVUS findings; No calcification group (n=50), spotty group (n=56) who had a lesion containing only small calcium deposits within an arc <90° and diffuse group (n=56) who had a diffuse calcified lesion with an arc ≥ 90° in ≥ 1 cross-sectional image of the lesion.RESULTS:
No calcification group was younger than spotty and diffuse groups (54.4 ± 13.0 years vs. 61.1 ± 10.7 years and 64.2 ± 9.9 years, p=0.011 and p<0.001, respectively). No calcification group had some degree of dense calcium (5. 7 ± 6.9 mm(3)) by VH-IVUS analysis. Furthermore, calcified volume by VH-IVUS in no calcification group was similar to those in spotty group (5.7 ± 6.9 mm(3) vs. 5.4 ± 4.4mm(3)). Dense calcium volume was correlated directly with plaque volume (r=0.65, p<0.001), fibrous volume (r=0.54, p<0.001), fibro-fatty volume (r=0.29, p<0.001) and lipid core volume (r=0.77, p<0.001). In multiple regression analysis, lipid core volume (ß=0.287, 95% confidence interval (CI) 0.187-0.388, p<0.001) was an independent predictor of dense calcium volume.CONCLUSIONS:
This study showed that coronary calcium can be present even if invisible in gray scale IVUS and associated with lipid core volume, which is a characteristic of plaque vulnerability.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença da Artéria Coronariana
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Cálcio
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Ultrassonografia de Intervenção
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Calcificação Vascular
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Intervenção Coronária Percutânea
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article