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Prenatal intrarenal neuroblastoma mimicking a mesoblastic nephroma: a case report.
Garnier, Sarah; Maillet, Olivier; Haouy, Stéphanie; Saguintaah, Magalie; Serre, Isabelle; Galifer, René-Benoit; Forgues, Dominique; Guibal, Marie-Pierre; Allal, Hossein; Sabatier, Edith; Kalfa, Nicolas.
Afiliação
  • Garnier S; Département de chirurgie viscérale et urologique pédiatrique, Pôle enfant, Hôpital Lapeyronie, 34295 Montpellier, France.
J Pediatr Surg ; 47(8): e21-3, 2012 Aug.
Article em En | MEDLINE | ID: mdl-22901938
Mesoblastic nephroma is by far the most frequent intrarenal fetal tumor. To the best of our knowledge, we report the first case of a newborn with an intrarenal neuroblastoma that was discovered prenatally. An intrarenal echogenic and homogenous mass was observed on routine prenatal ultrasonography, corroborated by magnetic resonance imaging, in a 30-week gestation fetus. A male weighing 3280 g was born with elevated blood pressure and cardiac failure. Postnatal ultrasound confirmed a left intrarenal tumor with microcalcifications and perirenal adenopathy. An open total left nephrectomy by laparotomy was performed. The pathologic study reported that the mass was an intrarenal neuroblastoma with local and regional invasion. Immediate postoperative urine analysis revealed a high level of vanillylmandelic acid, and blood samples showed high levels of normetanephrine. The purpose of this report is to demonstrate that prenatal intrarenal neuroblastoma can clinically and radiologically mimick a mesoblastic nephroma. High blood pressure, calcifications, and lymphadenopathy on ultrasound should raise the index of suspicion for a possible malignant process. Preoperative measurement of urinary vanillylmandelic acid (VMA) and metanephrines should be performed if the diagnosis is in doubt.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ultrassonografia Pré-Natal / Nefroma Mesoblástico / Erros de Diagnóstico / Neoplasias Renais / Neuroblastoma Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Humans / Male / Newborn Idioma: En Ano de publicação: 2012 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ultrassonografia Pré-Natal / Nefroma Mesoblástico / Erros de Diagnóstico / Neoplasias Renais / Neuroblastoma Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Humans / Male / Newborn Idioma: En Ano de publicação: 2012 Tipo de documento: Article