Wide-field retinal imaging in the management of noninfectious posterior uveitis.
Am J Ophthalmol
; 154(5): 908-911.e2, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22935598
ABSTRACT
PURPOSE:
To determine whether the use of ultra wide-field imaging changes the management or determination of disease activity in patients with noninfectious posterior uveitis.DESIGN:
Prospective, observational case series.METHODS:
setting:
Divisions of Retina and Ocular Immunology at single academic medical center. patient population Total of 43 patients with noninfectious posterior uveitis seen by 4 investigators at the Wilmer Eye Institute. procedures Each patient underwent standard clinical examination, followed by ultra wide-field scanning laser ophthalmoscope (SLO) imaging and angiography. Investigators successively determined disease activity and management decisions based on clinical examination, examination plus simulated 30- or 60-degree fluorescein angiography (FA) (obtained by physically narrowing the field of view of the wide-field images), examination plus ultra wide-field SLO images, and examination plus wide-field FA. main outcomemeasures:
The primary outcome was the percentage of patients whose management changed based on the availability of wide-field imaging, compared with standard examination and imaging. The secondary outcome was detection of disease activity with and without wide-angle imaging.RESULTS:
Management was altered in 7 of 43 patients (16%) based on examination and limited FA, whereas 21 of 43 patients (48%) had management change with the use of the ultra wide-field imaging and angiography (P < .001). Disease activity was detected in 22 of 43 patients (51%) based on examination and simulated conventional imaging, and in 27 of 43 (63%) with wide-field imaging (P = .27).CONCLUSIONS:
The index study, with several design limitations, has suggested that ultra wide-field imaging may alter management decisions compared to standard-of-care imaging and clinical examination. Additional studies, including longitudinal evaluations, are needed to determine whether these findings, or the subsequent management alterations, may improve patient outcomes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oftalmoscopia
/
Retina
/
Angiofluoresceinografia
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Uveíte Posterior
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Adult
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Humans
/
Male
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article