EC144 is a potent inhibitor of the heat shock protein 90.

Shi, Jiandong; Van de Water, Ryan; Hong, Kevin; Lamer, Ryan B; Weichert, Kenneth W; Sandoval, Cristina M; Kasibhatla, Srinivas R; Boehm, Marcus F; Chao, Jianhua; Lundgren, Karen; Timple, Noelito; Lough, Rachel; Ibanez, Gerardo; Boykin, Christina; Burrows, Francis J; Kehry, Marilyn R; Yun, Theodore J; Harning, Erin K; Ambrose, Christine; Thompson, Jeffrey; Bixler, Sarah A; Dunah, Anthone; Snodgrass-Belt, Pamela; Arndt, Joseph; Enyedy, Istvan J; Li, Ping; Hong, Victor S; McKenzie, Andres; Biamonte, Marco A

Shi, Jiandong; Van de Water, Ryan; Hong, Kevin; Lamer, Ryan B; Weichert, Kenneth W; Sandoval, Cristina M; Kasibhatla, Srinivas R; Boehm, Marcus F; Chao, Jianhua; Lundgren, Karen; Timple, Noelito; Lough, Rachel; Ibanez, Gerardo; Boykin, Christina; Burrows, Francis J; Kehry, Marilyn R; Yun, Theodore J; Harning, Erin K; Ambrose, Christine; Thompson, Jeffrey; Bixler, Sarah A; Dunah, Anthone; Snodgrass-Belt, Pamela; Arndt, Joseph; Enyedy, Istvan J; Li, Ping; Hong, Victor S; McKenzie, Andres; Biamonte, Marco A.

Afiliação

Shi J; Biogen Idec, 5200 Research Place, San Diego, California 92122, USA.

J Med Chem ; 55(17): 7786-95, 2012 Sep 13.

Article em En | MEDLINE | ID: mdl-22938030

Assuntos

Proteínas de Choque Térmico HSP90/antagonistas & inibidores; Pirimidinas/farmacologia; Pirróis/farmacologia; Humanos; Difração de Raios X

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirróis / Proteínas de Choque Térmico HSP90 Limite: Humans Idioma: En Ano de publicação: 2012 Tipo de documento: Article

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