Chromolithic method development, validation and system suitability analysis of ultra-sound assisted extraction of glycyrrhizic acid and glycyrrhetinic acid from Glycyrrhiza glabra.
Nat Prod Commun
; 7(8): 991-4, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22978213
ABSTRACT
An ultrasound-assisted extraction and chromolithic LC method was developed for simultaneous determination of glycyrrhizic acid (GA) and glycyrrhetinic acid (GL) from the root extract of Glycyrrhizza glabra using RPLC-PDA. The developed method was validated according to the International Conference on Harmonisation. The method exhibited good linearity (r2 > 0.9989) with high precision and achieved good accuracies between 97.5 to 101.3% of quantitative results. The method is more sensitive and faster (resolved within ten minutes) than the earlier developed methods using normal LC columns.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácido Glicirrízico
/
Fracionamento Químico
/
Ácido Glicirretínico
/
Glycyrrhiza
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article