Yeast-mediated xanthone synthesis through oxidative intramolecular cyclization.
Org Lett
; 14(19): 5054-7, 2012 Oct 05.
Article
em En
| MEDLINE
| ID: mdl-22984826
ABSTRACT
Benzoylphloroglucinol derivatives are natural products showing diverse biological activities that could be modulated by structural modifications. For this purpose, we studied the biotransformation of guttiferone A and of maclurin using a combinatorial approach for screening active microorganism strains. We found a novel and unexpected yeast-catalyzed oxidation that has selectively given a new oxy-guttiferone A and norathyriol.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Leveduras
/
Xantonas
/
Antimaláricos
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article