One-pot transition-metal-free synthesis of dibenzo[b,f]oxepins from 2-halobenzaldehydes.
Org Lett
; 14(19): 5102-5, 2012 Oct 05.
Article
em En
| MEDLINE
| ID: mdl-22984846
ABSTRACT
A one-pot transition-metal-free, base-mediated synthesis of dibenzo[b,f]oxepins was developed. The reaction of 2-halobenzaldehydes with (2-hydroxyphenyl)acetonitriles proceeds via a sequential aldol condensation and intramolecular ether formation reaction in the presence of Cs(2)CO(3) and molecular sieves in toluene.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oxepinas
/
Benzaldeídos
/
Benzeno
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article