Shortened menstrual cycles in LCD manufacturing workers.
Occup Med (Lond)
; 63(1): 45-52, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-23012346
ABSTRACT
BACKGROUND:
Many chemical agents used in liquid crystal display (LCD) manufacturing have been evaluated in animal studies of female reproductive toxicity. Knowledge of their reproductive toxicity in humans is scant.AIMS:
To determine the effect of organic solvents on menstrual cycle characteristics of workers in LCD manufacturing.METHODS:
Cross-sectional study of female premenopausal workers in an LCD plant in Taiwan. Menstrual cycle characteristics were assessed from self-administered questionnaires, and chemical exposure was assessed using hand-held volatile organic compound (VOC) monitors with 24h canister sampling.RESULTS:
There was a response rate of 94%, and the final study population after exclusions was 288. Canister sampling found many chemical compounds with potential reproductive effects in the fabrication areas of the plant. Concentrations of total VOC were higher in the panel and module fabrication areas than in other areas of the plant. The prevalence of short menstrual cycles (>24 days) was higher in panel workers (adjusted odds ratio [OR] 7.68; 95% confidence interval [CI] 1.51-39.15) and module workers (adjusted OR 8.38; 95% CI 1.72-40.95) than in array fabrication workers and office workers.CONCLUSIONS:
We found evidence for a possible link between repeated exposure to multiple organic solvents such as ethanol and acetone and increased prevalence of short menstrual cycles in premenopausal women.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Solventes
/
Exposição Ocupacional
/
Cristais Líquidos
/
Compostos Orgânicos Voláteis
/
Indústrias
/
Ciclo Menstrual
/
Distúrbios Menstruais
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article