In-office treatment for dentin hypersensitivity: a systematic review and network meta-analysis.
J Clin Periodontol
; 40(1): 53-64, 2013 Jan.
Article
em En
| MEDLINE
| ID: mdl-23057701
ABSTRACT
AIM:
Dentin hypersensitivity, caused by the exposure and patency of dentinal tubules, can affect patients' quality of life. The aim of this study was to undertake a systematic review and a network meta-analysis, comparing the effectiveness in resolving dentin hypersensitivity among different in-office desensitizing treatments. MATERIALS ANDMETHODS:
A literature search was performed with electronic databases and by hand until December 2011. The included trials were divided into six treatment groups as placebo, physical occlusion, chemical occlusion, nerve desensitization, laser therapy and combined treatments. The treatment effects between groups were estimated with standardized mean differences by using a Bayesian network meta-analysis.RESULTS:
Forty studies were included. The standardized mean difference between placebo and physical occlusion was -2.57 [95% credible interval (CI) -4.24 to -0.94]; placebo versus chemical occlusion was -2.33 (95% CI -3.65 to -1.04); placebo versus nerve desensitization was -1.72 (95% CI -4.00 to 0.52); placebo versus laser therapy was -2.81 (95% CI -4.41 to -1.24); placebo versus combined treatment was -3.47 (95% CI -5.99 to -0.96). The comparisons of the five active treatments showed no significant differences.CONCLUSIONS:
The results from network meta-analysis showed that most active treatment options had significantly better treatment outcome than placebo.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Permeabilidade da Dentina
/
Sensibilidade da Dentina
/
Dessensibilizantes Dentinários
Tipo de estudo:
Clinical_trials
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article