Quantitative assay of free and total carnitine using tandem mass spectrometry.
Clin Chim Acta
; 186(3): 383-90, 1990 Jan 31.
Article
em En
| MEDLINE
| ID: mdl-2311263
ABSTRACT
A new, specific method for isotope dilution assay of total and free carnitine in urine has been developed. The method utilizes fast atom bombardment ionization with tandem mass spectrometry and requires minimal sample preparation. It compared well with radioenzymatic assay in terms of specificity, precision and accuracy, but was much more convenient in terms of analysis time and sample throughput. The new method is also applicable to the determination of free and short-chain total carnitine in plasma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espectrometria de Massas
/
Carnitina
Limite:
Humans
Idioma:
En
Ano de publicação:
1990
Tipo de documento:
Article