Effect of early diabetes on the expression of alpha-1 adrenergic receptors in aorta and carotid arteries of Wistar Kyoto and spontaneously hypertensive rats.
Clin Exp Hypertens
; 35(6): 389-95, 2013.
Article
em En
| MEDLINE
| ID: mdl-23134281
ABSTRACT
Hypertension and diabetes have been related to noradrenergic system impairment, especially to the response mediated by alpha-1 receptors. The aim of this work was to investigate possible changes in the expression of alpha-1 adrenergic receptors in aorta and carotid arteries of Wistar Kyoto and spontaneously hypertensive rats after 4 weeks of the onset of diabetes. Our results suggest that early diabetes modifies the expression of alpha-1 adrenergic receptors in aorta and carotid arteries of both WKY and SHR strains in a different way.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Receptores Adrenérgicos alfa 1
/
Diabetes Mellitus Experimental
/
Angiopatias Diabéticas
/
Hipertensão
Limite:
Animals
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article