Secrets of drug resistance in NSCLC exposed by new molecular definition of EMT.
Clin Cancer Res
; 19(1): 3-5, 2013 Jan 01.
Article
em En
| MEDLINE
| ID: mdl-23172883
ABSTRACT
Non-small cell lung carcinoma (NSCLC) metastasis and drug resistance has been associated with epithelial-to-mesenchymal transition (EMT). This study reports the development of a robust gene expression signature of EMT in NSCLC and reveals new insights into the key molecular events that underlie EMT and drug resistance in NSCLC.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Proto-Oncogênicas
/
Receptores Proteína Tirosina Quinases
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Carcinoma Pulmonar de Células não Pequenas
/
Resistencia a Medicamentos Antineoplásicos
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Inibidores de Proteínas Quinases
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Transição Epitelial-Mesenquimal
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Neoplasias Pulmonares
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article