Aerosol transmission of chronic wasting disease in white-tailed deer.
J Virol
; 87(3): 1890-2, 2013 Feb.
Article
em En
| MEDLINE
| ID: mdl-23175370
ABSTRACT
While the facile transmission of chronic wasting disease (CWD) remains incompletely elucidated, studies in rodents suggest that exposure of the respiratory mucosa may be an efficient pathway. The present study was designed to address this question in the native cervid host. Here, we demonstrate aerosol transmission of CWD to deer with a prion dose >20-fold lower than that used in previous oral inoculations. Inhalation of prions may facilitate transmission of CWD and, perhaps, other prion infections.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aerossóis
/
Doença de Emaciação Crônica
Limite:
Animals
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article