Ramariolides A-D, antimycobacterial butenolides isolated from the mushroom Ramaria cystidiophora.
J Nat Prod
; 75(12): 2178-82, 2012 Dec 28.
Article
em En
| MEDLINE
| ID: mdl-23205944
ABSTRACT
Four butenolides, ramariolides A-D (1-4), have been isolated from the fruiting bodies of the coral mushroom Ramaria cystidiophora. Their structures were elucidated by analysis of 1D and 2D NMR data and a single-crystal X-ray diffraction analysis of 1, and their absolute configurations were established using Mosher's method. The major metabolite, ramariolide A (1), which contains an unusual spiro oxiranebutenolide moiety, showed in vitro antimicrobial activity against Mycobacterium smegmatis and Mycobacterium tuberculosis.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
4-Butirolactona
/
Agaricales
/
Antituberculosos
Limite:
Animals
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article