Non-enzymatic dynamic kinetic resolution of secondary aryl alcohols: planar chiral ferrocene and ruthenium catalysts in cooperation.
Angew Chem Int Ed Engl
; 52(2): 502-4, 2013 Jan 07.
Article
em En
| MEDLINE
| ID: mdl-23225694
ABSTRACT
"Ruth" helps iron! A novel method for the non-enzymatic dynamic kinetic resolution (DKR) of secondary aryl alcohols by the use of the planar chiral ferrocene derivative (+)-1 in combination with the ruthenium racemization catalyst 2 yields acetylated alcohols in high enantioselectivity and yield. This development opens opportunities for new developments in the field of non-enzymatic dynamic kinetic resolution.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rutênio
/
Compostos Ferrosos
/
Álcoois
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article