[Four cases of meningeal metastasis originating from breast cancer].
Gan To Kagaku Ryoho
; 39(12): 1917-9, 2012 Nov.
Article
em Ja
| MEDLINE
| ID: mdl-23267929
ABSTRACT
Carcinomatous meningitis due to breast cancer is comparatively rare in Japan. Here, we report 4 cases of carcinomatous meningitis due to breast cancer. Meningeal metastasis was present in only 1 of the 4 cases, and the other 3 cases were associated with brain metastasis. Meningeal metastasis frequently causes symptoms associated with intracranial hypertension. Gadolinium-enhanced magnetic resonance imaging and cerebrospinal fluid cytology were useful for the diagnosis of meningeal metastasis. Multidisciplinary therapy, such as radiation and chemotherapy, was performed. Two of the 4 patients were treated with combined intrathecal administration of methotrexate and whole brain radiation. The quality of life was improved by multidisciplinary therapy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Quimiorradioterapia
/
Neoplasias Meníngeas
Limite:
Female
/
Humans
/
Middle aged
Idioma:
Ja
Ano de publicação:
2012
Tipo de documento:
Article