Smoking as a predictor of negative outcome in diaphyseal fracture healing.
Int Orthop
; 37(5): 883-7, 2013 May.
Article
em En
| MEDLINE
| ID: mdl-23392346
ABSTRACT
PURPOSE:
The purpose of this study was to evaluate the impact of tobacco abuse in the consolidation of fractures.METHODS:
We retrospectively identified all patients with a diaphyseal fracture (femur, tibia, or humerus), between January 1999 and December 2010, in our orthopaedic trauma registry (Erasme hospital, Brussels, Belgium). Thirty-eight diaphyseal nonunions (ten femurs, 16 tibias and 12 humerus) were identified. Each nonunion was paired (on age, sex and location) with two control-healed fractures (76 control patients). The chi-squared test and a binary logistic regression were used for statistical analysis.RESULTS:
In multivariate analysis, smoking (tobacco use) was significantly associated with nonunion, whether the fracture was open or closed (p < 0.01). In univariate analysis, open fracture was associated with a higher risk of nonunion (p < 0.05), while external fixation was associated with better bone healing (p < 0.05).CONCLUSION:
Tobacco is confirmed as a deleterious factor for diaphyseal bone healing.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fumar
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Consolidação da Fratura
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Fraturas Ósseas
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Fraturas não Consolidadas
Tipo de estudo:
Etiology_studies
/
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article