[Subarachnoidal hemorrhage and multiple vascular cerebral abnormalities in ß-thalassemia major]. / Hémorragie sous-arachnoïdienne et anomalies vasculaires cérébrales multiples au cours d'une ß-thalassémie majeure.

ABSTRACT

ß-thalassemia is a genetic hemoglobinopathy, which can cause hypercoagulability, vessel wall damages and thromboembolic events. Spontaneous subarachnoidal hemorrhages are not commonly described in this affection. We report subarachnoidal hemorrhage, observed during the post-partum period in a 27-year-old woman suffering from ß-thalassemia major. Brain MRI revealed complex vascular abnormalities intracranial carotid occlusion, carotid micro-aneurisms, abnormally developed deep perforators and cortical arteries.