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ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems.
Kazarian, Sergei G; Chan, K L Andrew.
Afiliação
  • Kazarian SG; Department of Chemical Engineering, Imperial College London, SW7 2AZ, UK. s.kazarian@imperial.ac.uk
Analyst ; 138(7): 1940-51, 2013 Apr 07.
Article em En | MEDLINE | ID: mdl-23400222
Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopic imaging is a highly versatile, label free and non-destructive chemical imaging method which can be applied to study a wide range of samples and systems. This review summarises some of the recent advances and applications of this imaging method in the area of biomedical studies, including examples of section of aorta, skin tissue and live cells. Two of the major advantages of measuring in ATR mode are the opportunity to measure samples that absorb strongly in the IR spectrum, such as aqueous systems, without significant sample preparation and the ability to increase the spatial resolution of the measured image. The implications of these advantages as well as some limitations of this imaging approach are discussed and a brief outlook at some of the possible future developments in this area is provided.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectroscopia de Infravermelho com Transformada de Fourier / Análise de Célula Única Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espectroscopia de Infravermelho com Transformada de Fourier / Análise de Célula Única Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2013 Tipo de documento: Article